The four-octave, semi-weighted keyboard offers velocity sensitivity and channel aftertouch, while the control panel offers knob-per-function control with no menu diving. There are 500 permanent factory programs and 500 user programs which are organized into 10 banks of 100 presets. The OB-6 offers an ideal combination of portability and power for the project studio or the gigging musician.

The OB-6 from Sequential is a modern, all-analog 6-voice polyphonic synthesizer that pays tribute to Tom Oberheim's SEM 4-voice and 8-voice synthesizers, but with several enhancements. The synth features true voltage-controlled oscillators, a classic Oberheim-inspired 2-pole, state-variable resonant filter, amplifiers, envelopes, and an LFO. Additional enhancements include studio-quality effects, a polyphonic step-sequencer, and an arpeggiator; all of which can be synchronized internally or via external MIDI clock.